Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69666 | 0.84 | RXRA (0.70) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL4140084 | 0.82 | EGFR (0.64) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL71526 | 0.82 | RXRA (0.58) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL71773 | 0.82 | PARP10 (0.59) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL31241237 | 0.81 | LMNA (0.59) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL69503 | 0.81 | RXRA (0.57) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL16929834 | 0.81 | LMNA (0.59) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL6483625 | 0.81 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL9679321 | 0.80 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDRXRA | |
| SCHEMBL27472542 | 0.78 | RXRA (0.55) | NPC1RAB9ASMN1; SMN2HPGDRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |