Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217188 | 0.84 | KDM5A (0.60) | KDM5ACTSLCTSBCTSK | |
| SCHEMBL5223407 | 0.83 | KDM5A (0.57) | KDM5ACTSLCTSBCTSKUSP30 | |
| SCHEMBL5223393 | 0.83 | KDM5A (0.57) | KDM5ACTSLCTSBCTSKUSP30 | |
| SCHEMBL994466 | 0.81 | CTSL (0.63) | KDM5ACTSLCTSBCTSKNPSR1 | |
| Bicarbonate SCHEMBL185416 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2A | |
| SCHEMBL185580 | 0.78 | SMYD3 (0.54) | MEN1KMT2A | |
| SCHEMBL19133764 | 0.78 | HDAC4 (0.47) | — | |
| SCHEMBL25403939 | 0.77 | CYP1A2 (0.57) | KDM5ACTSLCTSBCTSKUSP30 | |
| SCHEMBL10212135 | 0.77 | HDAC4 (0.52) | DRD4 | |
| SCHEMBL25400740 | 0.77 | CYP1A2 (0.57) | KDM5ACTSLCTSBCTSKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |