SCHEMBL27870207

SCHEMBL27870207

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nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
AKR1B1 P15121 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858560 0.82 LMNA (0.43) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL28257916 0.82 LMNA (0.43) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5575462 0.80 USP2 (0.33) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL19512303 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL16915296 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL25264497 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL460069 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL20597593 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL3645294 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL599601 0.78 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104004776-A Microbial production of l-ascorbic acid DSM IP ASSESTS BV 2014-08-27 CN claimed
CN-1882691-B Process for the microbial production of L-ascorbic acid DSM IP ASSETS BV 2014-05-28 CN claimed
CN-110506111-A Trehalose phosphorylase C LECTA GMBH 2019-11-26 CN disclosed
CN-104004776-A Microbial production of l-ascorbic acid DSM IP ASSESTS BV 2014-08-27 CN disclosed
CN-102471763-B Fructosyl amino acid oxidase HOFFMANN LA ROCHE 2014-07-09 CN disclosed
CN-1882691-B Process for the microbial production of L-ascorbic acid DSM IP ASSETS BV 2014-05-28 CN disclosed
CN-102471763-A Fructosyl amino acid oxidase HOFFMANN LA ROCHE 2012-05-23 CN disclosed