SCHEMBL599601

SCHEMBL599601

O=C[C@@](O)(F)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
PDE4A P27815 1/20 0.34
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
AKR1B1 P15121 1/20 0.31
KDM4E B2RXH2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6795503 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL25264497 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL28985161 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL671071 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL98729 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
SCHEMBL28197 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
SCHEMBL27561548 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
Water SCHEMBL28186002 0.85 AKR1B1 (0.32) LMNAL3MBTL1AKR1B1
SCHEMBL968310 0.81 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL457880 0.81 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119744179-A Conjugates for targeted therapy 梁碧惠 2025-04-01 CN claimed
EP-4504267-A1 CONJUGATE FOR TARGETING THERAPY National Taiwan University (TW) 2025-02-12 EP claimed
WO-2023195839-A1 CONJUGATE FOR TARGETING THERAPY NATIONAL TAIWAN UNIVERSITY (TW) 2023-10-12 WO claimed
US-20230310618-A1 CONJUGATE FOR TARGETING THERAPY NATIONAL TAIWAN UNIVERSITY (TW) 2023-10-05 US claimed
EP-2445506-B1 THE USE OF SPINOSYNS AND SPINOSYN COMPOSITIONS AGAINST DISEASES CAUSED BY PROTOZOANS, VIRAL INFECTIONS AND CANCER ENTARCO SA (GR) 2014-12-31 EP claimed
US-8653043-B2 Enhanced neoglycosides through neoglycosylation and methods of use thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-02-18 US claimed
US-20130184330-A1 COMPOSITIONS AND METHODS FOR INDUCING CANCER CELL DEATH UNIVERSITY OF MIAMI (US) 2013-07-18 US claimed
US-20120108530-A1 Enhanced Neoglycosides Through Neoglycosylation and Methods of Use Thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-05-03 US claimed
US-20120094946-A1 GLYCOSYLATED CHLORAMBUCIL ANALOGS AND USES THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-04-19 US claimed
WO-2012024234-A1 COMPOSITIONS AND METHODS FOR INDUCING CANCER CELL DEATH UNIVERSITY OF MIAMI (US) 2012-02-23 WO claimed
US-20120039805-A1 Therapeutics And Methods For Treating Neoplastic Diseases Comprising Determining The Level Of Caveolin-1 And/Or Caveolin-2 In A Stromal Cell Sample PANGEA BIOSCIENCES, INC. 2012-02-16 US claimed
WO-2010096627-A1 THERAPEUTICS AND METHODS FOR TREATING NEOPLASTIC DISEASES COMPRISING DETERMINING THE LEVEL OF CAVEOLIN-1 AND/OR CAVEOLIN-2 IN A STROMAL CELL SAMPLE LISANTI MICHAEL P (US) 2010-08-26 WO claimed
WO-2010080863-A1 ENHANCED NEOGLYCOSIDES THROUGH NEOGLYCOSYLATION AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-07-15 WO claimed
EP-1322304-A4 MANIPULATION OF OXIDATIVE PHOSPHORYLATION FOR HYPERSENSITIZING TUMOR CELLS TO GLYCOLYTIC INHIBITORS LAMPIDIS THEODORE J (US) 2008-06-25 EP claimed
US-7160865-B2 Heterocyclic alcohols such as 2-deoxy-D-glucose or 5-thio-D-glucose, used as anticarcinogenic agents or angiogenesis inhibitors; glycolysis antagonists LAMPIDIS THEODORE J 2007-01-09 US claimed
US-20060025351-A1 Cancer treatment including glycolytic inhibitors LAMPIDIS THEODORE J 2006-02-02 US claimed
US-20050043250-A1 Cancer treatment including glycolytic inhibitors LAMPIDIS THEODORE J (US) 2005-02-24 US claimed
EP-1322304-A1 MANIPULATION OF OXIDATIVE PHOSPHORYLATION FOR HYPERSENSITIZING TUMOR CELLS TO GLYCOLYTIC INHIBITORS Lampidis, Theodore J. (US) 2003-07-02 EP claimed
WO-2001082926-A1 MANIPULATION OF OXIDATIVE PHOSPHORYLATION FOR HYPERSENSITIZING TUMOR CELLS TO GLYCOLYTIC INHIBITORS LAMPIDIS THEODORE J (US) 2001-11-08 WO claimed
WO-1998025940-A1 INHIBITORS OF GLYCOSYLTRANSFERASES THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025351-A1 Cancer treatment including glycolytic inhibitors HIF1AN, ALDOA, G6PD LMNA 4687/4885L3MBTL1 941/4885TDP1 2578/4885
US-20050043250-A1 Cancer treatment including glycolytic inhibitors HIF1AN, ALDOA, G6PD LMNA 4687/4885L3MBTL1 941/4885TDP1 2578/4885
US-20120094946-A1 GLYCOSYLATED CHLORAMBUCIL ANALOGS AND USES THEREOF CD22, UGGT1, UGCG LMNA 4698/4885L3MBTL1 264/4885TDP1 3929/4885
US-20120108530-A1 Enhanced Neoglycosides Through Neoglycosylation and Methods of Use Thereof BET1, GALE, ENGASE LMNA 3923/4885L3MBTL1 2087/4885TDP1 2444/4885
US-20230310618-A1 CONJUGATE FOR TARGETING THERAPY FOLH1, CD44, SLC10A1 LMNA 3750/4885L3MBTL1 1068/4885TDP1 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.