Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346898 | 0.88 | P2RX7 (0.41) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL30074233 | 0.87 | CES2 (0.47) | CES2CES1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL28897673 | 0.86 | CES2 (0.46) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL28469181 | 0.85 | CES2 (0.49) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL29655352 | 0.83 | CTSK (0.53) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL19928251 | 0.80 | CYP2C19 (0.52) | CES2CES1KMT2AKDM4ECYP2C19 | |
| SCHEMBL27582532 | 0.79 | STS (0.40) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL6036662 | 0.79 | KDM4E (0.48) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL9860856 | 0.78 | MAPK1 (0.50) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL30138490 | 0.78 | MAPK1 (0.46) | CES2CES1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370867-B | Rubber composition containing modified polybutadiene rubber and tire | BRIDGESTONE CORP | 2012-09-05 | — | — | CN | disclosed |