SCHEMBL27870291

SCHEMBL27870291

NCc1ccccc1OC(=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DPP4 P27487 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.38
EPHX1 P07099 1/20 0.38
CFD P00746 1/20 0.38
PLG P00747 1/20 0.38
PLAU P00749 1/20 0.38
F11 P03951 1/20 0.38
KLKB1 P03952 1/20 0.38
F7 P08709 1/20 0.38
TPSB2 P20231 1/20 0.38
HRH1 P35367 1/20 0.37
CXCL8 P10145 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PNMT P11086 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27870290 0.90 KDM4E (0.41) KDM4ESMN1; SMN2DPP4TSHREPHX1
SCHEMBL9616117 0.85 KDM4E (0.44) KDM4ESMN1; SMN2DPP4TSHRCFD
SCHEMBL7064539 0.83 L3MBTL1 (0.47) KDM4EATMTDP1TSHRL3MBTL1
Oxalic Acid SCHEMBL7254227 0.82 PTGS2 (0.51) KDM4ETDP1TSHRL3MBTL1CYP1A2
SCHEMBL27638622 0.82 ELANE (0.45) KDM4ESMN1; SMN2ATMTDP1TSHR
SCHEMBL27471665 0.81 MEN1 (0.41) KDM4ESMN1; SMN2DPP4TSHREPHX1
SCHEMBL27364543 0.80 KMT2A (0.58) SMN1; SMN2TDP1TSHRMEN1KMT2A
SCHEMBL2910938 0.79 PTGS2 (0.52) KDM4ETDP1TSHRCYP1A2CYP2C9
SCHEMBL28064699 0.79 L3MBTL1 (0.40) KDM4ESMN1; SMN2DPP4TSHREPHX1
SCHEMBL27365378 0.79 KMT2A (0.42) KDM4ESMN1; SMN2DPP4TSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102473775-A Sealing material for solar cell SUMITOMO CHEMICAL CO 2012-05-23 CN disclosed