Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.74 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484839 | 0.88 | HTR6 (0.77) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL2483723 | 0.86 | HTR6 (1.00) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL1848333 | 0.82 | HTR6 (0.71) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL2482386 | 0.81 | HTR6 (1.00) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL1844113 | 0.79 | HTR6 (0.73) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL2787028 | 0.78 | HTR6 (0.74) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL2485886 | 0.78 | SIRT6 (0.77) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL12259171 | 0.76 | DCTPP1 (0.78) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL20241847 | 0.76 | HTR6 (0.74) | HTR6SIRT6MAPTCYP1A2CYP3A4 | |
| SCHEMBL2484016 | 0.76 | SIRT6 (0.77) | HTR6SIRT6MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118347-A2 | O-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |