Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703731 | 0.81 | MAPT (0.38) | LMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27832762 | 0.81 | FPR2 (0.36) | — | |
| SCHEMBL27853597 | 0.79 | RAB9A (0.35) | LMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27828605 | 0.79 | KMT2A (0.41) | LMNAGAAALDH1A1 | |
| SCHEMBL9900065 | 0.78 | RAB9A (0.38) | LMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27917120 | 0.78 | KMT2A (0.32) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27917123 | 0.78 | HSD17B10 (0.40) | LMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27917153 | 0.77 | TXNRD1 (0.33) | — | |
| SCHEMBL9900188 | 0.75 | MAPT (0.31) | ALDH1A1 | |
| SCHEMBL1703930 | 0.75 | MEN1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414207-B | Fluorinated aminotriazole derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-09-30 | — | — | CN | disclosed |
| CN-102414207-A | Fluorinated aminotriazole derivatives | ACTELION PHARMACEUTICALS LTD | 2012-04-11 | — | — | CN | disclosed |