Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793625 | 1.00 | TLR8 (0.68) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL168398 | 0.98 | TLR8 (0.69) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL28162401 | 0.93 | TLR8 (0.69) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL28214718 | 0.89 | TLR8 (0.62) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL1325742 | 0.88 | TLR8 (0.64) | TLR8 | |
| SCHEMBL1326148 | 0.88 | TLR8 (0.60) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL1325776 | 0.88 | TLR8 (0.60) | TLR8KCNH2 | |
| SCHEMBL28146814 | 0.85 | TLR8 (0.62) | TLR8ALDH1A1GLAMAPTHPGD | |
| Formamide SCHEMBL28501493 | 0.85 | TLR8 (0.62) | TLR8ALDH1A1GAA | |
| SCHEMBL27512951 | 0.84 | TLR8 (0.68) | TLR8KDM4EUSP2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102464613-B | Synthetic method of quinoline derivative | UNIV CHINA PETROLEUM | 2015-07-01 | — | — | CN | disclosed |
| CN-102464613-A | Synthesis method of quinoline derivative | UNIV CHINA PETROLEUM | 2012-05-23 | — | — | CN | disclosed |