SCHEMBL28793625

SCHEMBL28793625

CCCCCCCCc1cc2ccccc2nc1CCCCCCCC

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 10/20 0.68
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LIPG Q9Y5X9 1/20 0.44
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27870558 1.00 TLR8 (0.68) TLR8KDM4EUSP2ALDH1A1GLA
SCHEMBL168398 0.98 TLR8 (0.69) TLR8KDM4EUSP2ALDH1A1GLA
SCHEMBL28162401 0.93 TLR8 (0.69) TLR8ALDH1A1GLAMAPTHPGD
SCHEMBL28214718 0.89 TLR8 (0.62) TLR8ALDH1A1GLAMAPTHPGD
SCHEMBL1325742 0.88 TLR8 (0.64) TLR8
SCHEMBL1326148 0.88 TLR8 (0.60) TLR8KDM4EUSP2ALDH1A1GLA
SCHEMBL1325776 0.88 TLR8 (0.60) TLR8KCNH2
SCHEMBL28146814 0.85 TLR8 (0.62) TLR8ALDH1A1GLAMAPTHPGD
Formamide SCHEMBL28501493 0.85 TLR8 (0.62) TLR8ALDH1A1GAA
SCHEMBL27512951 0.84 TLR8 (0.68) TLR8KDM4EUSP2ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102276799-B Quinoxaline unit-containing fluorene copolymer, and preparation method and application thereof OCEANS KING LIGHTING TECH CO 2014-05-28 CN disclosed
CN-102276799-A Quinoxaline unit-containing fluorene copolymer, and preparation method and application thereof 2011-12-14 CN disclosed