Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 10/20 | 0.42 |
| ▸ | CTSL | P07711 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870578 | 0.81 | GPR119 (0.52) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL665470 | 0.77 | MAOB (0.39) | — | |
| SCHEMBL1103885 | 0.77 | GPR119 (0.48) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL6125659 | 0.76 | GPR119 (0.52) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL13180108 | 0.74 | GPR119 (0.50) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL387110 | 0.74 | GPR119 (0.56) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL3651380 | 0.72 | GPR119 (0.44) | GPR119CTSKCTSLCTSBCTSS | |
| SCHEMBL1199503 | 0.71 | NCF1 (0.52) | — | |
| SCHEMBL22772 | 0.71 | — | — | |
| SCHEMBL3336979 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863794-B | Quinazoline derivatives as angiogenesis inhibitors | ASTRAZENECA AB | 2012-04-25 | — | — | CN | disclosed |