Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870684 | 0.74 | ALDH1A1 (0.52) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10917698 | 0.72 | ALDH1A1 (0.51) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12998894 | 0.72 | HPGD (0.54) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10918694 | 0.72 | ALDH1A1 (0.54) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27852212 | 0.71 | MMP1 (0.41) | RAB9AHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8413466 | 0.71 | RAB9A (0.55) | RAB9AHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4103378 | 0.70 | CYP2C19 (0.53) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9430080 | 0.70 | POLB (0.58) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL24805790 | 0.70 | MAPT (0.57) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1107021 | 0.69 | GAA (0.62) | RAB9AHPGDALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646678-B | heteroaryl derivatives | NIPPON SHINYAKU CO LTD | 2012-05-30 | — | — | CN | disclosed |