⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310143 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL544750 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL14820445 | 0.82 | ADRB2 (0.46) | — | |
| SCHEMBL24116097 | 0.79 | — | — | |
| SCHEMBL22135578 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL170911 | 0.75 | — | — | |
| SCHEMBL863208 | 0.73 | EPHX2 (0.33) | — | |
| SCHEMBL317547 | 0.73 | EPHX2 (0.33) | — | |
| SCHEMBL863289 | 0.73 | EPHX2 (0.33) | — | |
| SCHEMBL987686 | 0.73 | EPHX2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133984-B2 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids | PENTABASE APS (DK) | 2012-03-13 | — | — | US | disclosed |
| US-20100121056-A1 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | HUMAN GENETIC SIGNATURES PTY. LTD. (AU) | 2010-05-13 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| WO-2009097578-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-06 | — | — | WO | disclosed |