Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887166 | 1.00 | DRD2 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27726484 | 1.00 | DRD2 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27904323 | 0.93 | SLC18A3 (0.40) | SLC18A3PDE4BRIPK1HTTRAB9A | |
| SCHEMBL28318315 | 0.87 | ALDH1A1 (0.40) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27629052 | 0.87 | ALDH1A1 (0.40) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL28685326 | 0.87 | ALDH1A1 (0.49) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27979570 | 0.86 | SLC18A3 (0.33) | SLC18A3ALDH1A1LMNAGAARIPK1 | |
| SCHEMBL27872124 | 0.85 | DRD3 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27318172 | 0.85 | SLC18A3 (0.44) | SLC18A3RIPK1 | |
| SCHEMBL27937102 | 0.83 | SLC6A2 (0.40) | PROKR1HSD11B1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254623-A | SUBSTITUTED BENZAMIDES | HOFFMANN LA ROCHE | 2016-01-20 | — | — | CN | disclosed |
| CN-102686563-A | Substituted benzamide derivatives | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | disclosed |