SCHEMBL27872124 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	DRD3	P35462	4/20	0.41

▸	DRD4	P21917	3/20	0.39

▸	DRD2	P14416	2/20	0.39

▸	BCL9	O00512	2/20	0.39

▸	CTNNB1	P35222	2/20	0.39

▸	DRD1	P21728	1/20	0.39

▸	DRD5	P21918	1/20	0.39

▸	SIGMAR1	Q99720	3/20	0.39

▸	NFKB1	P19838	1/20	0.39

▸	PRCP	P42785	1/20	0.39

▸	EBP	Q15125	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27682015	0.87	RIPK1 (0.39)	DRD2BCL9CTNNB1
SCHEMBL27887166	0.85	DRD2 (0.37)	DRD3DRD4DRD2DRD1DRD5
SCHEMBL27726484	0.85	DRD2 (0.37)	DRD3DRD4DRD2DRD1DRD5
SCHEMBL27870976	0.85	DRD2 (0.37)	DRD3DRD4DRD2DRD1DRD5
SCHEMBL28685326	0.85	ALDH1A1 (0.49)	DRD3DRD4DRD2DRD1DRD5
SCHEMBL27913877	0.82	PROKR1 (0.37)	BCL9CTNNB1
SCHEMBL27937102	0.82	SLC6A2 (0.40)	—
SCHEMBL28104620	0.81	HRH3 (0.44)	DRD3DRD4DRD2BCL9CTNNB1
SCHEMBL1439746	0.80	PDE4B (0.51)	BCL9CTNNB1
SCHEMBL27904323	0.79	SLC18A3 (0.40)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-102711473-A	Bruton's tyrosine kinase inhibitors	BIOGEN IDEC INC	2012-10-03	—	—	CN	disclosed