Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1256889 | 0.99 | DRD2 (0.44) | DRD2ADRA1ADRD3SIGMAR1ACHE | |
| SCHEMBL1256254 | 0.84 | KDR (0.57) | KDRATRFYNNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1257055 | 0.82 | KDR (0.56) | KDRATRFYNNPC1RAB9A | |
| SCHEMBL9958722 | 0.82 | SIGMAR1 (0.45) | DRD2ADRA1ADRD3SIGMAR1ACHE | |
| SCHEMBL1257965 | 0.82 | DRD2 (0.43) | DRD2ADRA1ADRD3SIGMAR1ACHE | |
| Acetic Acid SCHEMBL1256468 | 0.79 | SIGMAR1 (0.43) | DRD2ADRA1ADRD3SIGMAR1ACHE | |
| SCHEMBL1255230 | 0.79 | SIGMAR1 (0.48) | SIGMAR1HRH3FYNNPC1RAB9A | |
| SCHEMBL1256469 | 0.77 | SIGMAR1 (0.41) | DRD2ADRA1ADRD3SIGMAR1ACHE | |
| SCHEMBL1257160 | 0.77 | KDR (0.50) | DRD2ADRA1ADRD3HRH3KDR | |
| SCHEMBL1256232 | 0.76 | CD274 (0.51) | DRD2ADRA1ADRD3ACHEKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102470127-A | Biaryl compounds and methods of use thereof | AMBIT BIOSCIENCES CORP | 2012-05-23 | — | — | CN | disclosed |