SCHEMBL2787130

SCHEMBL2787130

Oc1cc2c3ccccc3c3ccccc3c2cn1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.38
IDO1 P14902 2/20 0.36
TDO2 P48775 1/20 0.35
HPRT1 P00492 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HSP90AA1 P07900 2/20 0.34
HTT P42858 2/20 0.34
HSP90AB1 P08238 1/20 0.34
POLB P06746 1/20 0.34
RAD52 P43351 1/20 0.34
PKM P14618 1/20 0.33
CYP11B1 P15538 1/20 0.33
ERN1 O75460 1/20 0.33
NQO2 P16083 1/20 0.32
GPR3 P46089 1/20 0.32
MYC P01106 1/20 0.31
MAX P61244 1/20 0.31
PADI4 Q9UM07 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840867 0.87
SCHEMBL24188616 0.74 ALDH1A1 (0.52) TRPM4HPRT1KDM4EPOLBCYP11B1
SCHEMBL8341742 0.74 ALDH1A1 (0.52) TRPM4IDO1TDO2HPRT1KDM4E
SCHEMBL16230966 0.71 CYP1A2 (0.52) KDM4EGPR3
SCHEMBL31180481 0.71 AHR (0.55) IDO1TDO2KDM4EGPR3
SCHEMBL10644440 0.71 GABRP (0.64) KDM4EPKMLMNA
SCHEMBL2748581 0.70 KDM4E (0.38) KDM4EHSP90AA1HTTLMNA
SCHEMBL2747883 0.70 HTT (0.38) KDM4EHTTPKM
SCHEMBL2749439 0.70 KDM4E (0.38) KDM4E
SCHEMBL147859 0.68 CYP1A2 (0.54) KDM4ENQO2GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2520571-B1 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-08-17 EP disclosed
EP-2520571-B1 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-08-17 EP disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
EP-2429997-B1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2014-01-15 EP disclosed
EP-2429997-B1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2014-01-15 EP disclosed
EP-2520571-A1 2-azatriphenylene materials for organic light emitting diodes Universal Display Corporation (US) 2012-11-07 EP disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed
WO-2010132524-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 WO disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES DDT, NR2E3, ALKBH2 TRPM4 2231/4885IDO1 180/4885TDO2 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.