Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopurine SCHEMBL29901502 | 0.89 | ALDH1A1 (0.48) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL5631 | 0.89 | ALDH1A1 (0.48) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL28283405 | 0.87 | ALDH1A1 (0.47) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL1528157 | 0.81 | ALDH1A1 (0.42) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL10551243 | 0.81 | ALDH1A1 (0.42) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL8343847 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL383841 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL4342851 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL20305128 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RXFP1KDM4EMAPTAPEX1 | |
| 2-Aminopurine SCHEMBL9014624 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RXFP1KDM4EMAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279974-A1 | Nucleosides With Non-Natural Bases as Anti-Viral Agents | IDENIX PHARMACEUTICALS, INC. | 2010-11-04 | — | — | US | disclosed |
| EP-1898934-A1 | NUCLEOSIDES WITH NON-NATURAL BASES AS ANTI-VIRAL AGENTS | Idenix (Cayman) Limited (KY) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007144686-A1 | NUCLEOSIDES WITH NON-NATURAL BASES AS ANTI-VIRAL AGENTS | IDENIX (CAYMAN) LIMITED (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20060040944-A1 | 5-Aza-7-deazapurine derivatives for treating Flaviviridae | IDENIX PHARMACEUTICALS, INC. | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040944-A1 | 5-Aza-7-deazapurine derivatives for treating Flaviviridae | TPMT, NUDT15, DUSP5 | ALDH1A1 909/4885RXFP1 4733/4885KDM4E 312/4885 |
| US-20100279974-A1 | Nucleosides With Non-Natural Bases as Anti-Viral Agents | PNP, NSUN2, NME2 | ALDH1A1 3538/4885RXFP1 4588/4885KDM4E 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.