Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP13 | P45452 | 6/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 5/20 | 0.43 |
| ▸ | MMP12 | P39900 | 5/20 | 0.43 |
| ▸ | MMP14 | P50281 | 5/20 | 0.43 |
| ▸ | MMP16 | P51512 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647 | 0.79 | KDM4E (0.53) | KDM4ESMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL29157638 | 0.79 | KDM4E (0.54) | KDM4EL3MBTL1MEN1KMT2AMMP2 | |
| SCHEMBL27480641 | 0.79 | L3MBTL1 (0.69) | GAAKDM4EL3MBTL1MEN1POLB | |
| Water SCHEMBL3696220 | 0.78 | KDM4E (0.52) | KDM4ESMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL2702291 | 0.78 | KDM4E (0.52) | KDM4ESMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL6812015 | 0.78 | KDM4E (0.52) | KDM4ESMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL8577256 | 0.78 | LMNA (0.51) | KDM4ESMN1; SMN2L3MBTL1MEN1POLB | |
| SCHEMBL10335126 | 0.78 | L3MBTL1 (0.50) | KDM4ESMN1; SMN2L3MBTL1MEN1POLB | |
| SCHEMBL6567089 | 0.78 | KDM4E (0.52) | KDM4EL3MBTL1MEN1KMT2ALMNA | |
| Phthalic Acid SCHEMBL8994216 | 0.78 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482231-A | Sulfonic amide and sulfoximine-substituted diaryl-dihydropyrimidinones and usage thereof | Bayer Pharma AG | 2012-05-30 | — | — | CN | claimed |