Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871974 | 0.84 | P2RX7 (0.39) | KCNN4OPRL1P2RX7 | |
| SCHEMBL1808960 | 0.83 | OPRL1 (0.42) | KCNN4OPRL1 | |
| SCHEMBL1808442 | 0.81 | ALDH1A1 (0.39) | KCNN4P2RX7KLKB1 | |
| SCHEMBL1807100 | 0.77 | L3MBTL1 (0.39) | — | |
| SCHEMBL27882037 | 0.75 | OPRL1 (0.43) | OPRL1 | |
| SCHEMBL27872101 | 0.71 | TDP1 (0.39) | KLKB1 | |
| SCHEMBL27871912 | 0.70 | OPRL1 (0.40) | OPRL1P2RX7 | |
| SCHEMBL28797984 | 0.69 | OPRL1 (0.44) | OPRL1P2RX7 | |
| SCHEMBL11972707 | 0.67 | OPRL1 (0.39) | OPRL1P2RX7 | |
| SCHEMBL13248030 | 0.66 | KCNN4 (0.41) | KCNN4RXRAGRIN1GRIN2BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666550-A | Spiropiperidine compounds as ORL-1 receptor antagonists | LILLY CO ELI | 2012-09-12 | — | — | CN | disclosed |