Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | CA1 | P00915 | 2/20 | 0.82 |
| ▸ | CA2 | P00918 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guaiacol SCHEMBL27509885 | 0.93 | CA1 (0.86) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL27482331 | 0.92 | CA1 (0.69) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL11570825 | 0.91 | TP53 (0.75) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL21626 | 0.91 | — | — | |
| Guaiacol SCHEMBL671733 | 0.91 | CA2 (1.00) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL29454477 | 0.91 | — | — | |
| Guaiacol SCHEMBL2033828 | 0.90 | TP53 (0.67) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL28330363 | 0.88 | CA1 (0.86) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL25403512 | 0.88 | CA2 (0.95) | TSHRTP53CA1CA2MAPT | |
| Guaiacol SCHEMBL15553824 | 0.88 | CA2 (0.95) | TSHRTP53CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102483416-A | Means And Methods For Diagnosing Prostate Carcinomas | METANOMICS HEALTH GMBH DE | 2012-05-30 | — | — | CN | claimed |
| CN-102483416-A | Means And Methods For Diagnosing Prostate Carcinomas | METANOMICS HEALTH GMBH DE | 2012-05-30 | — | — | CN | disclosed |