Guaiacol

Guaiacol

SCHEMBL671733

COc1ccccc1O.COc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 1.00
CA1 P00915 3/20 1.00
TP53 P04637 2/20 1.00
TSHR P16473 1/20 1.00
MAPT P10636 4/20 0.68
ALDH1A1 P00352 4/20 0.68
LMNA P02545 3/20 0.68
MAPK1 P28482 3/20 0.68
KDM4E B2RXH2 3/20 0.68
CYP3A4 P08684 2/20 0.68
HPGD P15428 2/20 0.68
ALOX15 P16050 2/20 0.68
HSD17B10 Q99714 2/20 0.68
ALOX12 P18054 1/20 0.68
CA7 P43166 2/20 0.63
CA9 Q16790 2/20 0.63
CA12 O43570 2/20 0.63
CA4 P22748 2/20 0.63
CA14 Q9ULX7 2/20 0.63
MAOB P27338 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiacol SCHEMBL29454477 1.00
Guaiacol SCHEMBL21626 1.00
Guaiacol SCHEMBL16418214 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT
1,2-Dimethoxybenzene SCHEMBL8581123 0.97 CA1 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL30957249 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL25403512 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL8576299 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL7398872 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL11574553 0.97 CA1 (0.95) CA2CA1TP53TSHRMAPT
Guaiacol SCHEMBL15553824 0.97 CA2 (0.95) CA2CA1TP53TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104624225-A Low-temperature aqueous-phase catalyst for lignin phenol derivative hydrodeoxygenation and preparation method thereof UNIV NANKAI 2015-05-20 CN claimed
WO-2012168470-A1 METHOD FOR THE DETERMINATION OF THE CONCENTRATION OF VITAMIN B6 IN A SAMPLE BÜHLMANN LABORATORIES AG (CH) 2012-12-13 WO claimed
EP-1893187-B1 IMPROVED ANTIMICROBIAL PEROXIDASE COMPOSITIONS FLEN PHARMA N V (BE) 2008-11-19 EP claimed
CN-114989052-B Guaiacol-austempering compound and preparation method thereof 苏州大学 2024-07-19 CN disclosed
US-12011432-B2 Method of modulating ribonucleotide reductase CASE WESTERN RESERVE UNIVERSITY (US) 2024-06-18 US disclosed
CN-114989052-A Guaiazuo thioether compound and preparation method thereof 苏州大学 2022-09-02 CN disclosed
US-20210299095-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE CASE WESTERN RESERVE UNIVERSITY 2021-09-30 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
EP-3624596-A1 METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD International Flavors & Fragrances Inc. (US) 2020-03-25 EP disclosed
WO-2020018747-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE CASE WESTERN RESERVE UNIVERSITY (US) 2020-01-23 WO disclosed
CN-110218709-A A kind of heat-resisting laccase and its gene and application 福州大学 2019-09-10 CN disclosed
CN-1235922-C Water-absorbent resin and method for producing same NIPPON CATALYTIC CHEM IND (JP) 2006-01-11 CN disclosed
US-20050261523-A1 Preparation of (METH) acrylic acid and (METH) acrylic esters BASF AKTIENGESELLSCHAFT (DE) 2005-11-24 US disclosed
US-20050249851-A1 Taint removal from wine WINE NETWORKS TECHNOLOGY PTY. LTD. (AU) 2005-11-10 US disclosed
EP-0900775-B1 PROCESS FOR PRODUCING CATECHOL DERIVATIVES DAISO CO LTD (JP) 2004-07-28 EP disclosed
CN-1492884-A Water-absorbent resin and method for producing same ��ʽ�����ձ���ý 2004-04-28 CN disclosed
US-6080895-A Process of producing catechol derivatives DAISO CO., LTD. (JP) 2000-06-27 US disclosed
EP-0900775-A1 PROCESS FOR PRODUCING CATECHOL DERIVATIVES DAISO CO., LTD. (JP) 1999-03-10 EP disclosed
US-4145527-A QUALITATIVE ANALYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-03-20 US disclosed
US-4048236-A ORTHO-ALKOXYPHENOL, ALLYL HALIDE UBE INDUSTRIES, LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299095-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE RRM2, RRM2B, RRM1 CA2 2992/4885CA1 2716/4885TP53 492/4885
US-12011432-B2 Method of modulating ribonucleotide reductase RRM2, RRM2B, RRM1 CA2 2992/4885CA1 2716/4885TP53 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.