Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17011444 | 0.75 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2032760 | 0.75 | L3MBTL1 (0.54) | MEN1KMT2ARPS6KB1AURKACYP1A2 | |
| SCHEMBL1224382 | 0.75 | KDM4E (0.50) | MEN1KMT2ARPS6KB1AURKACYP1A2 | |
| SCHEMBL14730366 | 0.74 | MEN1 (0.48) | MEN1KMT2ARPS6KB1AURKACYP1A2 | |
| SCHEMBL11013921 | 0.73 | KDM4C (0.54) | MEN1KMT2ARPS6KB1AURKACYP1A2 | |
| SCHEMBL19422708 | 0.73 | VNN1 (0.52) | MEN1KMT2ARPS6KB1AURKAVNN1 | |
| SCHEMBL2032247 | 0.72 | ABL1 (0.52) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL26894623 | 0.72 | KDM4E (0.41) | CYP1A2CYP2C19CYP3A4CYP2D6TSHR | |
| SCHEMBL13530512 | 0.72 | MAPT (0.45) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1443534 | 0.72 | MEN1 (0.52) | MEN1KMT2ARPS6KB1AURKACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548980-A | 5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC | 2012-07-04 | — | — | CN | disclosed |
| CN-102497781-A | N1-substituted-5-fluoro-2-oxopyrimidinone-1(2H)-carboxamide derivatives | DOW AGROSCIENCES LLC | 2012-06-13 | — | — | CN | disclosed |