Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193800 | 0.84 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL29525553 | 0.84 | MAPK1 (0.33) | NPSR1 | |
| SCHEMBL31408631 | 0.83 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL29433993 | 0.81 | NPSR1 (0.35) | NPSR1 | |
| SCHEMBL27584019 | 0.73 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL3455318 | 0.72 | TDP1 (0.37) | TDP1L3MBTL1NPSR1 | |
| SCHEMBL2319028 | 0.72 | TDP1 (0.37) | TDP1L3MBTL1NPSR1 | |
| SCHEMBL7657865 | 0.71 | HSD11B1 (0.43) | — | |
| SCHEMBL7657874 | 0.71 | HSD11B1 (0.43) | — | |
| SCHEMBL3732250 | 0.70 | TDP1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666531-A | Heterocyclic-substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2012-09-12 | — | — | CN | disclosed |