Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 5/20 | 0.40 |
| ▸ | CCND1 | P24385 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787736 | 0.94 | MEN1 (0.45) | GOT1PTGS2TRPV1CDK4CCND1 | |
| SCHEMBL2787793 | 0.93 | GOT1 (0.44) | GOT1SIRT1PTGS2TRPV1CDK4 | |
| SCHEMBL2788385 | 0.90 | CDK4 (0.44) | GOT1SIRT1PTGS2TRPV1CDK4 | |
| SCHEMBL2787706 | 0.87 | GOT1 (0.44) | GOT1PTGS2TRPV1CDK4CCND1 | |
| SCHEMBL2788832 | 0.85 | MEN1 (0.41) | GOT1SIRT1PTGS2TRPV1CDK4 | |
| SCHEMBL2787635 | 0.85 | MAPT (0.47) | CDK4CCND1MEN1KMT2AMAPT | |
| SCHEMBL2790691 | 0.85 | MEN1 (0.45) | GOT1SIRT1PTGS2TRPV1CDK4 | |
| SCHEMBL2787930 | 0.85 | MEN1 (0.45) | CDK4CCND1MEN1KMT2AMAPT | |
| SCHEMBL2787992 | 0.84 | GOT1 (0.49) | GOT1PTGS2TRPV1CDK4CCND1 | |
| SCHEMBL9943282 | 0.83 | MC5R (0.47) | GOT1CDK4CCND1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2099815-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | Acure Pharma AB (SE) | 2009-09-16 | — | — | EP | claimed |
| WO-2008058679-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ACURE PHARMA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| US-8227502-B2 | Amides acting on the adenosine receptors | ANAMAR AB (SE) | 2012-07-24 | — | — | US | disclosed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ACURE PHARMA AB (SE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ADORA1, ADORA3, ADORA2B | GOT1 1175/4885SIRT1 2192/4885PTGS2 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.