Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687548 | 0.85 | FFAR2 (0.74) | RAB9ASMN1; SMN2NPC1TP53THRB | |
| Hydrochloric Acid SCHEMBL29855979 | 0.83 | FFAR2 (0.72) | RAB9ASMN1; SMN2NPC1TP53THRB | |
| SCHEMBL11627595 | 0.80 | ROCK1 (0.61) | RAB9ASMN1; SMN2NPC1TP53THRB | |
| SCHEMBL23657933 | 0.80 | PRKACA (0.61) | RAB9ASMN1; SMN2NPC1TP53HPGD | |
| SCHEMBL8987744 | 0.77 | RIOK2 (0.51) | RAB9AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL7470030 | 0.77 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1TP53THRB | |
| SCHEMBL10915238 | 0.76 | FFAR2 (0.58) | RAB9ASMN1; SMN2NPC1TP53THRB | |
| SCHEMBL24142977 | 0.76 | MEN1 (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL6013703 | 0.76 | FFAR2 (0.55) | SMN1; SMN2ALDH1A1LMNAMAPK1POLB | |
| SCHEMBL8808257 | 0.75 | KDR (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102516113-B | Series of diphenyl oxide derivatives and use of diphenyl oxide derivatives in preparation of anti-tuberculosis drugs | UNIV SICHUAN | 2014-04-09 | — | — | CN | disclosed |
| CN-102516113-A | A series of diphenyl oxide derivatives and use of diphenyl oxide derivatives in preparation of anti-tuberculosis drugs | UNIV SICHUAN | 2012-06-27 | — | — | CN | disclosed |