Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 7/20 | 0.51 |
| ▸ | GSK3A | P49840 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.51 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15155033 | 0.87 | RIOK2 (0.45) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8987796 | 0.82 | RIOK2 (0.53) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL27858347 | 0.81 | KMT2A (0.63) | LMNAGLSRAB9AKMT2AMEN1 | |
| SCHEMBL13491679 | 0.80 | GLS (0.48) | RIOK2GSK3AMAPK10LMNAROCK1 | |
| SCHEMBL8987836 | 0.79 | KMT2A (0.53) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL27874867 | 0.77 | RAB9A (0.62) | LMNAGLSRAB9AKMT2AMEN1 | |
| SCHEMBL8987787 | 0.76 | RIOK2 (0.50) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8988057 | 0.76 | MAPK10 (0.48) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8987764 | 0.76 | RIOK2 (0.51) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL14363132 | 0.76 | RAB9A (0.57) | RAB9AKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |