SCHEMBL278749

SCHEMBL278749

Oc1ccc(-c2ccc(O)cc2O)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.62
ESR1 P03372 3/20 0.52
ESR2 Q92731 3/20 0.52
TYR P14679 3/20 0.52
MAOA P21397 1/20 0.52
UGT1A1 P22309 1/20 0.52
MAOB P27338 1/20 0.52
CES2 O00748 1/20 0.50
DYRK1A Q13627 1/20 0.50
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
HPGD P15428 2/20 0.48
GAA P10253 2/20 0.48
HTT P42858 1/20 0.48
RUNX1 Q01196 1/20 0.48
CBFB Q13951 1/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29623114 1.00 ALOX5 (0.62) ALOX5ESR1ESR2TYRMAOA
SCHEMBL14850418 0.88 ALOX5 (0.65) ALOX5ESR1ESR2MAPTKDM4E
SCHEMBL11340793 0.88 ALOX5 (0.52) ALOX5ESR1ESR2TYRMAOA
SCHEMBL9250422 0.86 ALOX5 (0.62) ALOX5ESR1ESR2DYRK1AALDH1A1
SCHEMBL5687674 0.84 ALDH1A1 (0.50) ALOX5ESR1ESR2TYRMAOA
SCHEMBL29861377 0.84 ALOX5 (0.48) ALOX5ESR1ESR2TYRMAOA
SCHEMBL16196432 0.84 ALOX5 (0.48) ALOX5ESR1ESR2TYRMAOA
SCHEMBL19186914 0.84 ESR2 (0.65) ALOX5ESR1ESR2ALDH1A1MAPT
SCHEMBL16196429 0.82 ALOX5 (0.52) ALOX5ESR1ESR2TYRMAOA
SCHEMBL278379 0.82 ALOX5 (0.73) ALOX5ESR1ESR2HSD17B10HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487923-B1 HIGH STRENGTH RUBBER COMPOSITION MICHELIN & CIE (FR) 2023-06-28 EP claimed
EP-2323612-B1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS UNIGEN INC (US) 2019-07-10 EP claimed
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US claimed
US-9341949-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2016-05-17 US claimed
US-20160083322-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS UNIGEN, INC. (US) 2016-03-24 US claimed
US-20140322647-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2014-10-30 US claimed
EP-2323612-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS Unigen, Inc. (US) 2011-05-25 EP claimed
WO-2010011630-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS UNIGEN PHARMACEUTICALS, INC. (US) 2010-01-28 WO claimed
US-20100016347-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS UNIGEN PHARMACEUTICALS, INC. (US) 2010-01-21 US claimed
US-20090081589-A1 THICK FILM RESISTS MERCK PATENT GMBH (DE) 2009-03-26 US claimed
EP-0395346-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-11-27 EP claimed
US-5254432-A Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 US claimed
US-4323454-A CURED EPOXY RESIN, FILLER, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US claimed
US-4323453-A EPOXY RESIN CURED WITH AN IMIDAZOLE, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US claimed
US-4269952-A Preparation of glycidyl polyarylethers RHONE-POULENC INDUSTRIES (FR) 1981-05-26 US claimed
US-3931912-A Two-part hair dye or hair bleach package THE GILLETTE COMPANY (US) 1976-01-13 US claimed
EP-4702010-A1 PHOTOACTIVE COMPOUNDS Merck Patent GmbH (DE) 2026-03-04 EP disclosed
US-20250376552-A1 RESIN COMPOSITION, CURED SUBSTANCE, LAMINATE, MANUFACTURING METHOD FOR CURED SUBSTANCE, MANUFACTURING METHOD FOR LAMINATE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2025-12-11 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed
US-3931912-A Two-part hair dye or hair bleach package THE GILLETTE COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083322-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS TYR, TH, MAOB ALOX5 301/4885ESR1 3560/4885ESR2 3265/4885
US-20100016347-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS TYR, MAOB, TH ALOX5 287/4885ESR1 3933/4885ESR2 3531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.