Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807928 | 0.85 | MEN1 (0.56) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL31588115 | 0.81 | IDH2 (0.48) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL6502465 | 0.81 | IDH2 (0.56) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL30432445 | 0.81 | LMNA (0.60) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL31587567 | 0.80 | MEN1 (0.45) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL28533950 | 0.79 | KMT2A (0.49) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL31587418 | 0.76 | KMT2A (0.47) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL31587536 | 0.76 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL31587690 | 0.75 | LMNA (0.42) | MEN1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL4553592 | 0.74 | CYP1A2 (0.36) | L3MBTL1RAB9AALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102695416-A | Kinase inhibitors | GENOSCO | 2012-09-26 | — | — | CN | claimed |
| CN-102695416-A | Kinase inhibitors | GENOSCO | 2012-09-26 | — | — | CN | disclosed |