Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547476 | 0.84 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL5550694 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL4786365 | 0.82 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL2406119 | 0.79 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL5551984 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL4553592 | 0.77 | CYP1A2 (0.36) | ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5547459 | 0.77 | KDM4E (0.44) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL5550133 | 0.73 | KDM4E (0.45) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL17287922 | 0.73 | NPC1 (0.62) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL20236578 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334451-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2021-02-05 | — | — | CN | disclosed |