SCHEMBL278774

SCHEMBL278774

Cc1cc(-c2ccc(O)cc2)cc(C)c1O

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.70
CA2 P00918 1/20 0.70
ESR1 P03372 7/20 0.62
ABL1 P00519 3/20 0.56
ABCB1 P08183 3/20 0.56
BCR P11274 3/20 0.56
ESR2 Q92731 6/20 0.55
SENP1 Q9P0U3 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALOX5 P09917 1/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
HSD17B1 P14061 2/20 0.45
HSD17B2 P37059 2/20 0.45
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503537 1.00 CA1 (0.70) CA1CA2ESR1ABL1ABCB1
SCHEMBL17220670 1.00 CA1 (0.70) CA1CA2ESR1ABL1ABCB1
SCHEMBL17060490 0.92 CA1 (0.82) CA1CA2ESR1ABL1ABCB1
P-Cresol SCHEMBL15511799 0.88 CA1 (0.67) CA1CA2ESR1ABL1ABCB1
SCHEMBL28148470 0.85 ESR1 (0.62) CA1CA2ESR1ABL1ABCB1
SCHEMBL15445310 0.85 CA1 (0.70) CA1CA2ESR1MEN1KMT2A
SCHEMBL220910 0.84 CA1 (1.00) CA1CA2ESR1ESR2MEN1
SCHEMBL22804025 0.84 CA1 (1.00) CA1CA2ESR1ESR2MEN1
Phenol SCHEMBL7039341 0.83 CA1 (0.67) CA1CA2ESR2MEN1KMT2A
SCHEMBL3807600 0.82 CYP2C9 (0.78) CA1CA2ESR1ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101583686-A Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP (NL) 2009-11-18 CN claimed
US-20230331925-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-19 US disclosed
EP-4219589-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-02 EP disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
WO-2022065329-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN 三菱瓦斯化学株式会社 2022-03-31 WO disclosed
US-20200331828-A1 NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME UNIV ILLINOIS (US) 2020-10-22 US disclosed
US-20200224098-A1 POLYMERIZABLE MONOMER, LIQUID CRYSTAL COMPOSITION USING POLYMERIZABLE MONOMER, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-07-16 US disclosed
US-10703698-B2 Compounds which activate estrogen receptors and compositions and methods of using the same THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2020-07-07 US disclosed
US-20190002380-A1 NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2019-01-03 US disclosed
US-20170319993-A1 FINE FIBER MEDIA LAYER DONALDSON COMPANY, INC. 2017-11-09 US disclosed
US-7318852-B2 Bag house filter with fine fiber and spun bonded media DONALDSON COMPANY, INC. (US) 2008-01-15 US disclosed
US-7316723-B2 Air filter with fine fiber and spun bonded media DONALDSON COMPANY, INC. (US) 2008-01-08 US disclosed
US-20070283808-A1 AIR FILTER WITH FINE FIBER AND SPUN BONDED MEDIA DONALDSON COMPANY, INC. (US) 2007-12-13 US disclosed
US-20070271883-A1 layer of a polyester filter bag substrate, layer of fine fiber in the form of microfiber and nanofiber structures on the upstream surface, fine fiber is covered with a protective layer DONALDSON COMPANY, INC. (US) 2007-11-29 US disclosed
US-20070271891-A1 Fiber layer of an addition polymer and a hydrophobic additive in the form of a coating on the fine fibers; microfibers, nanofibers, fiber webs, fibrous mats, permeable structures such as membranes, coatings, films DONALDSON COMPANY, INC. (US) 2007-11-29 US disclosed
US-7270693-B2 Polymer, polymer microfiber, polymer nanofiber and applications including filter structures DONALDSON COMPANY, INC. (US) 2007-09-18 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-7179317-B2 Polymer, polymer microfiber, polymer nanofiber and applications including filter structures DONALDSON COMPANY, INC. (US) 2007-02-20 US disclosed
US-20070012007-A1 Addition or condensation polymer containing 2-25% of an additive comprising an aromatic oligomer having a molecular weight of 500-3000, especially a polyphenyl resin with p-tert-butylphenol, p-biphenol or bisphenol A units; improved stability and strength DONALDSON COMPANY, INC. (US) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703698-B2 Compounds which activate estrogen receptors and compositions and methods of using the same GPER1, ESRRG, ESR2 CA1 618/4885CA2 2016/4885ESR1 4/4885
US-20190002380-A1 NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME GPER1, ESRRG, ESR2 CA1 810/4885CA2 2607/4885ESR1 4/4885
US-20200331828-A1 NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME GPER1, ESRRG, ESR2 CA1 810/4885CA2 2607/4885ESR1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.