Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 15/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 15/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 15/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787356 | 0.87 | PDE1A (0.39) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2786536 | 0.83 | CDK1 (0.42) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2788889 | 0.76 | GSK3A (0.60) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2787166 | 0.69 | CDK1 (0.34) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL28195540 | 0.68 | L3MBTL1 (0.47) | PDE1APDE1BPDE1CL3MBTL1 | |
| SCHEMBL2787037 | 0.67 | CDK5 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2785280 | 0.65 | CYP11B1 (0.39) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2786751 | 0.65 | CCNB2 (0.49) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL29983324 | 0.62 | CYP19A1 (0.50) | PDE1APDE1BPDE1C | |
| SCHEMBL4102153 | 0.60 | PDE1B (0.44) | PDE1APDE1BPDE1CTLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |