Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787037 | 0.78 | CDK5 (0.41) | CDK1CDK2MAP4K4CDK9CCNB2 | |
| SCHEMBL2787754 | 0.69 | CCNB2 (0.39) | CDK1CCNB2CCNB1GSK3AGSK3B | |
| SCHEMBL2216872 | 0.65 | CDK1 (0.42) | CDK1CDK2MKNK1MKNK2MAP4K4 | |
| SCHEMBL2786751 | 0.63 | CCNB2 (0.49) | CDK1CCNB2CCNB1GSK3AGSK3B | |
| SCHEMBL1148699 | 0.61 | MAP4K4 (0.66) | CDK1CDK2MKNK1MKNK2MAP4K4 | |
| SCHEMBL1779054 | 0.61 | CCNB2 (0.48) | CDK1CCNB2CCNB1GSK3AGSK3B | |
| SCHEMBL5312790 | 0.61 | BACE1 (0.42) | — | |
| SCHEMBL11212892 | 0.60 | ADRB2 (0.39) | — | |
| SCHEMBL27727264 | 0.60 | MAPK1 (0.38) | CDC7 | |
| SCHEMBL253273 | 0.59 | LMNA (0.55) | PDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |