Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204819 | 0.77 | GABRA1 (0.42) | SRPK1 | |
| SCHEMBL354704 | 0.75 | — | — | |
| SCHEMBL6970853 | 0.75 | — | — | |
| SCHEMBL27930827 | 0.73 | KMT2A (0.40) | SCN9A | |
| SCHEMBL28311384 | 0.73 | PIK3CD (0.35) | PIK3CDF2RRIPK1ACACB | |
| Trifluoroacetic Acid SCHEMBL15923058 | 0.72 | ASPH (0.36) | PIK3CDPLA2G7MGLLABHD6SRPK1 | |
| SCHEMBL3642043 | 0.70 | F2R (0.40) | PIK3CDPLA2G7MGLLABHD6SRPK1 | |
| SCHEMBL554720 | 0.70 | CYP1A2 (0.50) | ACACB | |
| SCHEMBL27754289 | 0.69 | KMT2A (0.44) | ACACB | |
| SCHEMBL2170593 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064223-A | FXR (NR1H4) modulating compound of hydroxyl | 吉利德科学公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-104395309-A | Cyclic bridgehead ether dgat1 inhibitors | NOVARTIS AG | 2015-03-04 | — | — | CN | disclosed |
| CN-102781915-A | Diacylglycerol acyltransferase inhibitors | PIRAMAL LIFE SCIENCES LTD | 2012-11-14 | — | — | CN | disclosed |