SCHEMBL554720

SCHEMBL554720

CCOC(=O)c1cocn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
NAMPT P43490 1/20 0.46
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22265089 0.83 ACACB (0.34) CYP1A2NAMPTACACB
SCHEMBL22265097 0.81 F2R (0.34) CYP1A2NAMPTACACB
SCHEMBL28056849 0.81 ACACB (0.36) CYP1A2NAMPTACACB
SCHEMBL5163521 0.80 MGAM (0.44) NAMPTALDH1A1MAPTMEN1RAB9A
SCHEMBL29551483 0.79 F2R (0.33) NAMPTALDH1A1MAPTGABRPGABRD
SCHEMBL27965018 0.79 FBP1 (0.33) NAMPTALDH1A1MAPTGABRPGABRD
SCHEMBL354704 0.79
SCHEMBL4282448 0.77 FBP1 (0.55) NAMPTACACBTSHRGAA
SCHEMBL28204819 0.77 GABRA1 (0.42) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL9124321 0.75 KMT2A (0.52) CYP1A2NAMPTMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184954-B Degradable material added with starch 福建德绿新材料科技有限公司 2024-07-12 CN claimed
CN-118184954-A Degradable material added with starch 福建德绿新材料科技有限公司 2024-06-14 CN claimed
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN claimed
WO-2026103793-A1 TRICYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-21 WO disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12577211-B2 Probenecid compounds for the treatment of inflammasome-mediated lung disease BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-03-17 US disclosed
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2026-02-12 US disclosed
US-12545659-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-02-10 US disclosed
EP-4681712-A2 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-01-21 EP disclosed
EP-4126854-B1 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-12-03 EP disclosed
EP-4655284-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-12-03 EP disclosed
WO-2007093901-A1 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS PFIZER LIMITED (GB) 2007-08-23 WO disclosed
CN-101010323-A Bicyclononene derivatives as renin inhibitors ACTELION PHARMACEUTICALS LTD (CH) 2007-08-01 CN disclosed
EP-1786814-A1 BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS Actelion Pharmaceuticals Ltd. (CH) 2007-05-23 EP disclosed
WO-2006133216-A2 4-SUBSTITUTED ARYLAMINE DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS SMITHKLINE BEECHAM CORPORATION (US) 2006-12-14 WO disclosed
WO-2006021402-A1 BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS ACTELION PHARMACEUTICALS LTD. (CH) 2006-03-02 WO disclosed
US-6069132-A PYRIMIDOPHOSOHAZOLE RING SYSTEM OF GIVEN STRUCTURE, THE TRIVALENT PHOSPHORUS OF THE RING SUBSTITUTED WITH VARIOUS GROUPS; NEW CLASS OF PHOSPHORUS CONTAINING HETEROCYCLES WITH APPLICATION IN MEDICAL, AGRICULTURAL AND INDUSTRIAL USE ARONEX PHARMACEUTICALS, INC. 2000-05-30 US disclosed
WO-1999008688-A1 PHOSPHAZOLE-CONTAINING NUCLEOSIDE ANALOGS, RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN IN VITRO MEDICINAL TREATMENTS ARONEX PHARMACEUTICALS, INC. (US) 1999-02-25 WO disclosed
US-4785012-A OXAZOLE DERIVATIVES CONTAINING ALCOHOLS OR ESTERS SYNTEX CORPORATION (US) 1988-11-15 US disclosed
US-4039554-A FORAMIDOESTERS, HYDROXYACETONE, DYES, PESTICIDES, VITAMINS BASF AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545659-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK4 CYP1A2 4592/4885NAMPT 3507/4885ALDH1A1 4348/4885
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK4 CYP1A2 2456/4885NAMPT 2728/4885ALDH1A1 3721/4885
US-12577211-B2 Probenecid compounds for the treatment of inflammasome-mediated lung disease NLRP3, NLRP1, TLR4 CYP1A2 4044/4885NAMPT 3960/4885ALDH1A1 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.