Toluene

Toluene

SCHEMBL27878734

CCO[PH](=O)c1ccccc1C=O.Cc1ccccc1

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
TSHR P16473 2/20 0.38
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 4/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.35
GAA P10253 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11505580 0.78 ALDH1A1 (0.34) ALDH1A1HTT
SCHEMBL777147 0.73 TSHR (0.35) ALDH1A1TSHRKMT2AMEN1TDP1
Toluene SCHEMBL11343606 0.73 TSHR (0.48) ALDH1A1TSHRNPSR1LMNAKMT2A
Toluene SCHEMBL27749800 0.71 TSHR (0.46) ALDH1A1TSHRLMNAKMT2AMEN1
SCHEMBL313072 0.70 NPSR1 (0.35) ALDH1A1TSHRNPSR1KMT2AMEN1
SCHEMBL7916460 0.70 HTR2A (0.41) TSHRLMNASMN1; SMN2HPGDCYP2C9
SCHEMBL779740 0.70 MAPT (0.39) TSHRNPSR1HPGD
SCHEMBL12712829 0.69 ACHE (0.35) ALDH1A1TSHRKMT2AMEN1TDP1
SCHEMBL25332093 0.69 NPSR1 (0.34) ALDH1A1TSHRNPSR1KMT2AMEN1
Toluene SCHEMBL27361671 0.68 LMNA (0.58) ALDH1A1TSHRNPSR1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102498164-A Multilayer product comprising acrylate-containing coating BAYER MATERIALSCIENCE AG 2012-06-13 CN disclosed