SCHEMBL278794

SCHEMBL278794

Oc1cc(Cc2ccccc2)cc(O)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.65
BCL2 P10415 1/20 0.58
BCL2L1 Q07817 1/20 0.58
CALM1 P0DP23 1/20 0.57
PTPN1 P18031 3/20 0.52
PTPN2 P17706 1/20 0.52
PTPN6 P29350 1/20 0.52
HNF4A P41235 1/20 0.50
ALOX5 P09917 1/20 0.50
MPO P05164 1/20 0.49
ALOX15 P16050 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL28255494 0.88 IDH1 (0.53) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL18604568 0.87 PTPN1 (0.64) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL14549313 0.86 IDH1 (0.55) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL11408792 0.84 CA1 (0.52) IDH1PTPN1ALOX15MEN1HPGD
SCHEMBL31544990 0.84 IDH1 (0.63) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL14621022 0.82 TTR (0.53) IDH1BCL2BCL2L1CALM1
SCHEMBL31545825 0.82 IDH1 (0.61) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL28439714 0.82 CALM1 (0.52) IDH1BCL2BCL2L1CALM1PTPN1
SCHEMBL278270 0.81 ESR1 (0.67) IDH1ALOX15MEN1KMT2ACA1
SCHEMBL716420 0.81 IGF1R (0.55) IDH1BCL2BCL2L1ALOX15IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299545-A2 Branched polycarbonates containing tri-or tetra-hydroxy biphenil compounds, and process for preparing them ENICHEM S.p.A. (IT) 1989-01-18 EP claimed
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8269358-B2 Bis(aminophenol) derivative, process for producing same, polyamide resin, positive photosensitive resin composition, protective film, interlayer dielectric film, semiconductor device, and display element SUMITOMO BAKELITE COMPANY LIMITED (JP) 2012-09-18 US disclosed
US-8269358-B2 Bis(aminophenol) derivative, process for producing same, polyamide resin, positive photosensitive resin composition, protective film, interlayer dielectric film, semiconductor device, and display element SUMITOMO BAKELITE COMPANY LIMITED (JP) 2012-09-18 US disclosed
US-20120156614-A1 Novel Phenol Compounds and Positive Photosensitive Resin Composition Including the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-06-21 US disclosed
US-20120156614-A1 Novel Phenol Compounds and Positive Photosensitive Resin Composition Including the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-06-21 US disclosed
US-8198006-B2 Process for producing semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2012-06-12 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-7361445-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY (JP) 2008-04-22 US disclosed
US-7361445-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY (JP) 2008-04-22 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
US-4900803-A Branched polycarbonate from tri- or tetra-hydroxy biphenyl compounds ENICHEM TECNORESINE S.P.A. (IT) 1990-02-13 US disclosed
EP-0299545-A2 Branched polycarbonates containing tri-or tetra-hydroxy biphenil compounds, and process for preparing them ENICHEM S.p.A. (IT) 1989-01-18 EP disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120156614-A1 Novel Phenol Compounds and Positive Photosensitive Resin Composition Including the Same SUN2, TYR, PSMD2 IDH1 4667/4885BCL2 4508/4885BCL2L1 3212/4885
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 IDH1 2727/4885BCL2 4701/4885BCL2L1 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.