Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.33 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787942 | 1.00 | DPP4 (0.33) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2790207 | 0.91 | DPP4 (0.32) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2790204 | 0.91 | DPP4 (0.32) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL7893421 | 0.90 | ACKR3 (0.33) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2790244 | 0.90 | PROKR1 (0.35) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL7894446 | 0.90 | PROKR1 (0.35) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2789039 | 0.90 | GFER (0.34) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2789036 | 0.90 | GFER (0.34) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL2790247 | 0.90 | PROKR1 (0.35) | DPP4CFDPROKR1ALDH1A1TSHR | |
| SCHEMBL7900974 | 0.89 | PABPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |