Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897783 | 0.92 | PABPC1 (0.33) | PABPC1KLK5PTPN1 | |
| SCHEMBL7899253 | 0.91 | PABPC1 (0.32) | PABPC1KLK5PTPN1 | |
| SCHEMBL2791534 | 0.91 | MMP13 (0.34) | PABPC1KLK5 | |
| SCHEMBL7901258 | 0.91 | PABPC1 (0.33) | PABPC1KLK5 | |
| SCHEMBL2787942 | 0.89 | DPP4 (0.33) | — | |
| SCHEMBL2787940 | 0.89 | DPP4 (0.33) | — | |
| SCHEMBL7900833 | 0.88 | PABPC1 (0.34) | PABPC1KLK5PTPN1 | |
| SCHEMBL7898847 | 0.88 | MMP13 (0.35) | PABPC1KLK5MAPT | |
| SCHEMBL2790403 | 0.88 | PABPC1 (0.32) | PABPC1KLK5 | |
| SCHEMBL2790406 | 0.88 | PABPC1 (0.32) | PABPC1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |