Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.40 |
| ▸ | CBFB | Q13951 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989282 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL27670815 | 0.71 | ERN1 (0.44) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL6993258 | 0.68 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9135064 | 0.68 | HPGD (0.67) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL27813515 | 0.68 | KMT2A (0.52) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL2865511 | 0.67 | TDP1 (0.44) | ALDH1A1GAAHTT | |
| SCHEMBL9881101 | 0.67 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL14604208 | 0.67 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL27797719 | 0.66 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL1094712 | 0.66 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891709-B | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2012-11-21 | — | — | CN | disclosed |