Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 6/20 | 0.49 |
| ▸ | ELOC | Q15369 | 3/20 | 0.38 |
| ▸ | ELOB | Q15370 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.37 |
| ▸ | CDK2 | P24941 | 9/20 | 0.37 |
| ▸ | GSK3B | P49841 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879627 | 0.84 | VHL (0.65) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL15110656 | 0.81 | VHL (0.55) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL15110420 | 0.81 | VHL (0.55) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL20975701 | 0.81 | VHL (0.55) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL16276344 | 0.77 | VHL (0.48) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL20975657 | 0.77 | VHL (0.48) | VHLELOCELOBCCNE1CDK2 | |
| SCHEMBL27879617 | 0.75 | NR1H2 (0.30) | — | |
| SCHEMBL27896395 | 0.74 | LMNA (0.41) | KMT2A | |
| SCHEMBL27896413 | 0.74 | CYP1A2 (0.39) | ACACBP2RX7 | |
| SCHEMBL27896436 | 0.74 | LOXL2 (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |