Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879638 | 0.82 | LMNA (0.46) | LMNACYP1A2TSHRGFERALDH1A1 | |
| SCHEMBL28054871 | 0.74 | PIK3CD (0.39) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27879647 | 0.74 | VHL (0.49) | KMT2A | |
| SCHEMBL28054733 | 0.74 | — | — | |
| SCHEMBL27879622 | 0.74 | GFER (0.45) | LMNACYP1A2TSHRGFERALDH1A1 | |
| SCHEMBL27896399 | 0.71 | TSHR (0.42) | LMNATSHRALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27879617 | 0.70 | NR1H2 (0.30) | — | |
| SCHEMBL27896387 | 0.69 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2193740 | 0.68 | ALDH1A1 (0.36) | LMNATSHRGFERALDH1A1KDM4E | |
| SCHEMBL27896413 | 0.66 | CYP1A2 (0.39) | CYP1A2KDM4ECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |