Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 18/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 13/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 12/20 | 0.56 |
| ▸ | PSMB9 | P28065 | 12/20 | 0.56 |
| ▸ | PSMB6 | P28072 | 12/20 | 0.56 |
| ▸ | PSMB10 | P40306 | 12/20 | 0.56 |
| ▸ | PSMB11 | A5LHX3 | 11/20 | 0.56 |
| ▸ | PSMA7 | O14818 | 11/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 11/20 | 0.56 |
| ▸ | PSMA1 | P25786 | 11/20 | 0.56 |
| ▸ | PSMA2 | P25787 | 11/20 | 0.56 |
| ▸ | PSMA3 | P25788 | 11/20 | 0.56 |
| ▸ | PSMA4 | P25789 | 11/20 | 0.56 |
| ▸ | PSMA5 | P28066 | 11/20 | 0.56 |
| ▸ | PSMB4 | P28070 | 11/20 | 0.56 |
| ▸ | PSMB3 | P49720 | 11/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 11/20 | 0.56 |
| ▸ | PSMA6 | P60900 | 11/20 | 0.56 |
| ▸ | PSMA8 | Q8TAA3 | 11/20 | 0.56 |
| ▸ | PSMB7 | Q99436 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13364306 | 1.00 | LONP1 (0.56) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL2790181 | 0.84 | CTRB1 (0.46) | PSMB5PSMB8HDAC3CTRB1HDAC1 | |
| SCHEMBL2791228 | 0.82 | CTRB1 (0.49) | PSMB5PSMB8CTRB1 | |
| SCHEMBL13364075 | 0.82 | CTRB1 (0.49) | PSMB5PSMB8CTRB1 | |
| SCHEMBL2790267 | 0.81 | CTRB1 (0.45) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL13364307 | 0.81 | CTRB1 (0.45) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL13364076 | 0.81 | PSMB5 (0.52) | PSMB5 | |
| SCHEMBL2790655 | 0.81 | PSMB5 (0.52) | PSMB5 | |
| SCHEMBL13839315 | 0.79 | CTRB1 (0.60) | PSMB5PSMB8F2CTRB1 | |
| SCHEMBL2786862 | 0.79 | CTRB1 (0.60) | PSMB5PSMB8F2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120715-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120715-A1 | BETA-LACTAMASE INHIBITORS | GANAB, BPGM, BLVRB | LONP1 2831/4885PSMB5 1165/4885PSMB8 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.