Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 4/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870016 | 1.00 | CTRB1 (0.49) | CTRB1PSMB8PSMB5KDM4EHTT | |
| SCHEMBL2789280 | 0.91 | CTRB1 (0.51) | CTRB1PSMB8PSMB5HMGB1F2 | |
| SCHEMBL13839291 | 0.91 | CTRB1 (0.51) | CTRB1PSMB8PSMB5HMGB1F2 | |
| SCHEMBL2786862 | 0.90 | CTRB1 (0.60) | CTRB1PSMB8PSMB5KDM4EALDH1A1 | |
| SCHEMBL13839315 | 0.90 | CTRB1 (0.60) | CTRB1PSMB8PSMB5KDM4EALDH1A1 | |
| SCHEMBL2787674 | 0.88 | CTRB1 (0.49) | CTRB1PSMB8PSMB5KDM4EHTT | |
| SCHEMBL13839303 | 0.88 | CTRB1 (0.49) | CTRB1PSMB8PSMB5KDM4EHTT | |
| SCHEMBL12944967 | 0.87 | CTRB1 (0.51) | CTRB1PSMB8PSMB5HMGB1F2 | |
| SCHEMBL18827364 | 0.86 | CTRB1 (0.50) | CTRB1PSMB8PSMB5KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2769059 | 0.86 | CTRB1 (0.50) | CTRB1PSMB8PSMB5HMGB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286092-A1 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL, LTD. (BM) | 2010-11-11 | — | — | US | disclosed |
| WO-2010056827-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100120715-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120715-A1 | BETA-LACTAMASE INHIBITORS | GANAB, BPGM, BLVRB | CTRB1 196/4885PSMB8 1092/4885PSMB5 1165/4885 |
| US-20100286092-A1 | BETA-LACTAMASE INHIBITORS | GANAB, BPGM, BLVRB | CTRB1 196/4885PSMB8 1092/4885PSMB5 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.