Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14777016 | 0.90 | — | — | |
| SCHEMBL1276157 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL28413946 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL28055614 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL10438599 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL25191483 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL8955296 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL1157411 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL29010387 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL27799298 | 0.82 | THRB (0.44) | THRBMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786534-A | Preparation method of everolimus | SHANGSHAI SHYNDEC PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-102786534-A | Preparation method of everolimus | SHANGSHAI SHYNDEC PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |