SCHEMBL27880969

SCHEMBL27880969

COc1ccc(S(=O)(=O)OC(C)=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.55
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
GAA P10253 2/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
F2 P00734 3/20 0.51
PRSS1 P07477 3/20 0.51
PRSS2 P07478 3/20 0.51
PRSS3 P35030 3/20 0.51
HTT P42858 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28528003 0.85 F2 (0.56) PKMCA1CA2GAAMMP1
SCHEMBL443434 0.80 ALDH1A1 (0.53) PKMCA1CA2GAAMMP1
SCHEMBL28154895 0.80 ENPP2 (0.50) PKMCA1CA2GAAPOLB
SCHEMBL8843455 0.79 F2 (0.50) PKMCA1CA2GAAMMP1
SCHEMBL7607789 0.78 TSHR (0.52) PKMCA1CA2GAAMMP1
SCHEMBL28544964 0.78 F2 (0.46) PKMCA1CA2GAAMMP1
SCHEMBL26088501 0.78 ALDH1A1 (0.52) PKMCA1CA2GAAMMP1
SCHEMBL10412878 0.78 ALDH1A1 (0.52) PKMCA1CA2GAAMMP1
SCHEMBL31386568 0.78 TSHR (0.52) PKMCA1CA2GAAMMP1
SCHEMBL27880968 0.78 KMT2A (0.53) CA1CA2GAAMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102786373-B A kind of synthetic method of diazomethane compound SHENZHEN IPI BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2016-01-13 CN disclosed
CN-102786373-A Synthetic method of diazomethane compound SHENZHEN IPI BIOLOG TECHNOLOGY CO LTD 2012-11-21 CN disclosed