SCHEMBL27882575

SCHEMBL27882575

NC(=O)c1ccc(OP(=O)(O)Cc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 11/20 0.56
PLA2G10 O15496 1/20 0.51
PLA2G2A P14555 1/20 0.51
OPRK1 P41145 2/20 0.46
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
PARP15 Q460N3 3/20 0.44
PARP14 Q460N5 2/20 0.44
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44
PARP16 Q8N5Y8 1/20 0.44
PARP11 Q9NR21 1/20 0.44
PARP4 Q9UKK3 1/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3836998 0.84 SRC (0.57) KMT2ATSHRCYP2C19TDP1L3MBTL1
SCHEMBL16238910 0.83 ALDH1A1 (0.49) ALDH1A1MAPTL3MBTL1
SCHEMBL27882400 0.83 MAOA (0.47) MAPTTSHRL3MBTL1ANPEPLAP3
SCHEMBL27882402 0.82 LMNA (0.52) KMT2ATSHRCYP2C19ANPEPLAP3
SCHEMBL22321983 0.80 SRC (0.44) KMT2AMAPTTSHRANPEPLAP3
SCHEMBL22321985 0.80 ALDH1A1 (0.50) ALDH1A1MAPTTSHRPLAU
SCHEMBL27882403 0.79 PARP10 (0.65) PARP10PLA2G10PLA2G2APARP15PARP14
SCHEMBL27995302 0.75 PARP10 (0.60) PARP10PLA2G10PLA2G2ATSHRTDP1
SCHEMBL22322102 0.75 CA1 (0.59) ALDH1A1KMT2ACYP3A4TSHRCYP2C19
SCHEMBL3897575 0.75 PARP10 (0.59) PARP10PARP15PARP14ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558698-B High heat-resistant flame-retardant halogen-free thermoplastic resin and method for preparing same TIANJIN JINFA NEW MATERIAL CO LTD 2014-12-03 CN disclosed
CN-102558698-A High heat-resistant flame-retardant halogen-free thermoplastic resin and method for preparing same TIANJIN JINFA NEW MATERIAL CO LTD 2012-07-11 CN disclosed