Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.51 |
| ▸ | LIPC | P11150 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31224857 | 0.80 | FFAR4 (0.58) | ACACBFFAR4 | |
| SCHEMBL8285812 | 0.78 | ACACB (0.50) | ACACBFFAR4HRH1SIGMAR1 | |
| SCHEMBL7955313 | 0.77 | ACACB (0.49) | ACACBFFAR4 | |
| SCHEMBL20346991 | 0.77 | ALDH1A1 (0.64) | FFAR4LIPGLIPCHRH1 | |
| SCHEMBL13406711 | 0.76 | HRH3 (0.52) | ACACBFFAR4HRH1 | |
| SCHEMBL10262288 | 0.76 | HTR2C (0.60) | LIPGLIPC | |
| SCHEMBL10079036 | 0.76 | HTR2C (0.60) | LIPGLIPC | |
| SCHEMBL10261788 | 0.76 | HTR2C (0.60) | LIPGLIPC | |
| SCHEMBL10606002 | 0.75 | HRH3 (0.59) | — | |
| Hydrochloric Acid SCHEMBL10610517 | 0.74 | SMN1; SMN2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102827174-A | Preparation method for aldose reductase inhibitor fidarestat | LIANYUNGANG GUIKE PHARMACEUTICAL CO LTD | 2012-12-19 | — | — | CN | disclosed |