Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL28802761 | 0.87 | GPR35 (0.49) | ALDH1A1TDP1KMT2AMAPTRECQL | |
| SCHEMBL2680386 | 0.85 | MAPT (0.57) | ALDH1A1TDP1KMT2AMAPTRECQL | |
| SCHEMBL1306345 | 0.85 | MAPT (0.49) | ALDH1A1TDP1KMT2AMAPTRECQL | |
| SCHEMBL20175730 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TDP1KMT2AMAPTRECQL | |
| Fluorene SCHEMBL28402445 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPTMAOAHSD17B10 | |
| SCHEMBL6674292 | 0.79 | HSP90AA1 (0.50) | ALDH1A1TDP1KMT2AMAPTMCL1 | |
| SCHEMBL29577518 | 0.79 | HSD17B10 (0.67) | ALDH1A1TDP1KMT2ARECQLHSD17B10 | |
| SCHEMBL22566 | 0.79 | HSD17B10 (0.67) | ALDH1A1TDP1KMT2ARECQLHSD17B10 | |
| SCHEMBL16355165 | 0.79 | HSD17B10 (0.67) | ALDH1A1TDP1KMT2ARECQLHSD17B10 | |
| SCHEMBL7618863 | 0.77 | MAPT (0.58) | ALDH1A1KMT2AMAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617382-B | 2-amino-fluorene containing ester group and preparation method thereof | UNIV HARBIN ENG | 2014-01-29 | — | — | CN | claimed |
| CN-102617382-A | 2-amino-fluorene containing ester group and preparation method thereof | UNIV HARBIN ENG | 2012-08-01 | — | — | CN | claimed |
| CN-102617382-B | 2-amino-fluorene containing ester group and preparation method thereof | UNIV HARBIN ENG | 2014-01-29 | — | — | CN | disclosed |
| CN-102617382-A | 2-amino-fluorene containing ester group and preparation method thereof | UNIV HARBIN ENG | 2012-08-01 | — | — | CN | disclosed |