Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | PRKACG | P22612 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866910 | 0.78 | PRKACA (0.52) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL6695037 | 0.78 | PRKACA (0.55) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL11632150 | 0.73 | PRKACA (0.55) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL15413831 | 0.72 | PRKACA (0.46) | PRKACAPRKACGPRKACB | |
| SCHEMBL138439 | 0.72 | PRKACA (0.50) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL12804515 | 0.71 | PRKACA (0.49) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL28969630 | 0.71 | DRD2 (0.52) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL11632146 | 0.70 | PRKACA (0.52) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL28570762 | 0.70 | HTR1A (0.41) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL7963983 | 0.69 | DRD2 (0.46) | PRKACAPRKACGPRKACBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102625799-A | Heterocyclic compounds and their uses | AMGEN INC | 2012-08-01 | — | — | CN | disclosed |